Publications

Schwartz ER, Poulin RX, Mojib N, Kubanek J (2016) Chemical ecology of marine plankton. Natural Product Reports 33 (7):843-860. doi: 10.1039/C6NP00015K

Rasher DB, Stout EP, Engel S, Shearer TL, Kubanek J, Hay ME (2015) Marine and terrestrial herbivores display convergent chemical ecology despite 400 million years of independent evolution. Proceedings of the National Academy of Sciences 112:12110-12115. doi:10.1073/pnas.1508133112

Lunceford BE, Kubanek J (2015) Reception of aversive taste. Integrative and Comparative Biology 55:507-517. doi: 10.1093/icb/icv058

Selander E, Kubanek J, Hamberg M, Andersson MX, Cervin G, Pavia H (2015) Predator lipids induce paralytic shellfish toxins in bloom-­forming algae. Proceedings of the National Academy of Sciences 112:6395-6400. doi: 10.1073/pnas.1420154112

Poulson­-Ellestad K, Jones C, Roy J, Viant MR, Fernandez FM, Kubanek J, Nunn B (2014) Metabolomics and proteomics reveal impacts of chemically mediated competition on marine plankton. Proceedings of the National Academy of Sciences 111:9009­-9014. doi: 10.1073/pnas.1402130111

Poulson-­Ellestad K, McMillan E, Montaya PJ, Kubanek J (2014) Are offshore phytoplankton susceptible to Karenia brevis allelopathy? Journal of Plankton Research 36:1344-1356. doi:10.1093/plankt/fbu064

Penczykowski RM, Lemanski BCP, Sieg RD, Hall SR, Housley Ochs J, Kubanek J, Duffy MA (2014) Poor resource quality lowers transmission potential by changing foraging behaviour. Functional Ecology 28:1245­-1255. doi: 10.1111/1365­-2435.12238

Srinivasan B, Zhou H, Kubanek J, Skolnick J (2014) Experimental validation of FINDSITEcomb virtual ligand screening results for eight proteins yields novel nanomolar and picomolar binders. Journal of Cheminformatics 6:16. doi: 10.1186/1758-­2946-­6­-16

Kamio M, Schmidt M, Germann MW, Kubanek J, Derby CD (2014) The smell of moulting: N­ acetylglucosamino­1,5­-lactone is a premoult biomarker and candidate component of the courtship pheromone in the urine of the blue crab, Callinectes sapidus. Journal of Experimental Biology 217:1286­-1296. doi: 10.1242/jeb.099051

Teasdale ME, Prudhomme J, Torres M, Braley M, Cervantes S, Bhatia SC, La Clair JJ, Le Roch K, Kubanek J (2013) Pharmacokinetics, metabolism, and in vivo efficacy of the antimalarial natural product bromophycolide A. ACS Medicinal Chemistry Letters 4:989-­993.

Snare DJ, Fields AM, Snell TW, Kubanek J (2013) Lifespan extension of rotifers by treatment with red algal extracts. Experimental Gerontology 48:1420­-1427. doi:10.1016/j.exger.2013.09.007

Roy J, Poulson­Ellestad K, Sieg RD, Poulin R, Kubanek J (2013) Chemical ecology of the marine plankton. Natural Product Reports 30:1364-­1379. doi: 10.1039/C3NP70056A

Sieg RD, Wolfe K, Willey D, Kubanek J (2013) Multiple chemical defenses produced by Spartina alterniflora deter farming snails and their fungal crop. Marine Ecology Progress Series 488:35-­49. doi: 10.3354/meps10415

Sieg RD, Wolfe K, Willey D, Ortiz­Santiago V, Kubanek J (2013) Chemical defenses against herbivores and fungi limit establishment of fungal farms on salt marsh angiosperms. Journal of Experimental Marine Biology & Ecology 446:122­-130. doi: 10.1016/j.jembe.2013.05.007

Sieg RD, Kubanek J (2013) Chemical ecology of marine angiosperms: opportunities at the interface of marine and terrestrial systems. Journal of Chemical Ecology 39:687-­711. doi: 10.1007/s10886-013-0297-9

Andras TD, Alexander TS, Gahlena A, Parry RM, Fernandez FM, Kubanek J, Wang MD, Hay ME (2012) Seaweed allelopathy against coral: surface distribution of seaweed secondary metabolites by imaging mass spectrometry. Journal of Chemical Ecology 38:1203­-1214. doi: 10.1007/s10886-012-0204-9

Dove ADM, Leisen J, Zhou M, Byrne J, Lim­Hing K, Webb H, Gelbaum L, Viant M, Kubanek J, Fernandez FF (2012) Biomarkers of whale shark health – a metabolomic approach. PLoS ONE 7(11)e49379. doi:10.1371/journal.pone.0049379

Teasdale ME, Shearer TL, Engel S, Alexander TS, Fairchild CR, Le Roch K, Prudhomme J, Aalbersberg W, Hay ME, Kubanek J (2012) Bromophycoic acids: bioactive natural products from a Fijian red alga Callophycus sp. Journal of Organic Chemistry 77:8000­-8006. doi: 10.1021/jo301246x

Cervantes S, Stout EP, Prudhomme J, Engel S, Bruton M, Cervantes M, Carter D, Tae­Chang Y, Hay ME, Aalbersberg W, Kubanek J, Le Roch K (2012) High content live cell imaging for the discovery of new antimalarial marine natural products. BMC Infectious Diseases 12:1. doi:10.1186/1471-2334-12-1

Pavia H, Baumgartner F, Cervin G, Enge S, Kubanek J, Nylunch GM, Selander E, Svensson JR, Toth GB (2012) Chemical defences against herbivores. In: Chemical Ecology in Aquatic Systems, Bronmark C, Hansson LA, Eds., Oxford University Press, Oxford UK.

Rasher DB, Stout EP, Engel S, Kubanek J, Hay ME (2011) Macroalgal terpenes function as allelopathic agents against reef corals. Proceedings of the National Academy of Sciences 108:17726­-17731. doi: 10.1073/pnas.1108628108

Redshaw CH, Sutter DA, Lim­Hing K, Heckman ML, Jakobsson SL, Naar J, Kubanek J (2011) Tracking losses of brevetoxins on exposure to phytoplankton competitors: Ecological impacts. Harmful Algae 12:119­-124. doi: 10.1016/j.hal.2011.09.007

Zhang JL, Kubanek J, Hay ME, Aalbersberg W, Ye WC, Jiang RW (2011) Rapid identification of triterpenoid sulfates and hydroxy fatty acids including two new constituents from Tydemania expeditionis by liquid chromatography­mass spectrometry. Journal of Mass Spectrometry 46:908-­916. doi: 10.1002/jms.1969

Stout EP, Cervantes S, Prudhomme J, France S, La Clair JJ, Le Roch K, Kubanek J (2011) Bromophycolide A targets heme crystallization in the human malaria parasite Plasmodium falciparum. ChemMedChem 6:572­-577. doi: 10.1002/cmdc.201100252

Sieg RD, Poulson­-Ellestad KL, Kubanek J (2011) Chemical ecology of the marine plankton. Natural Product Reports 28:388­-399. doi: 10.1039/C0NP00051E

Stout EP, La Clair JJ, Snell TW, Shearer TL, Kubanek J (2010) Conservation of progesterone hormone function in invertebrate reproduction. Proceedings of the National Academy of Sciences 107:11859­-11864. doi: 10.1073/pnas.1006074107

Cohen SP, Vincent KK, Halstead­-Nussloch GE, Hatt H, Kubanek J, McCarty NA (2010) RL­-TGR, a co­receptor involved in aversive chemical signaling. Proceedings of the National Academy of Sciences 107:12339-­12344. doi: 10.1073/pnas.1000343107

Lin AS, Engel S, Smith BA, Fairchild CR, Aalbersberg W, Hay ME, Kubanek J (2010) Structure and biological evaluation of novel cytotoxic sterol glycosides from a marine red alga Peyssonnelia sp. Bioorganic and Medicinal Chemistry 18:8264­-8269. doi: 10.1016/j.bmc.2010.10.010

Redshaw CH, Sutter D, Myers TL, Naar J, Kubanek J (2010) Tracking losses of brevetoxins on exposure to phytoplankton competitors: Mechanistic insights. Aquatic Toxicology 100:365­-372.doi:10.1016/j.aquatox.2010.08.015

Poulson KL, Sieg RD, Prince EK, Kubanek J (2010) Allelopathic compounds of a red tide dinoflagellate have species­ specific and context ­dependent impacts on phytoplankton. Marine Ecology Progress Series 416:69-­78. doi: 10.3354/meps08788

Prince EK, Poulson KL, Myers TL, Sieg RD, Kubanek J (2010) Characterization of allelopathic compounds from the red tide dinoflagellate Karenia brevis. Harmful Algae 10:39­-48. doi: 10.1016/j.hal.2010.06.003

Stout EP, Prudhomme J, Le Roch K, Hay ME, Franzblau S, Fairchild CR, Aalbersberg W, Kubanek J (2010) Unusual antimalarial meroditerpenes from Fijian red algae. Bioorganic and Medicinal Chemistry Letters 20:5662­5665. doi: 10.1016/j.bmcl.2010.08.031

Blain JC, Mok YF, Kubanek J, Allingham JS (2010) Two molecules of lobophorolide cooperate to stabilize an actin dimer using both their ‘ring’ and ‘tail’ region. Chemistry & Biology 17:802-­807. doi:10.1016/j.chembiol.2010.06.010.

Lin, A­S, Stout EP, Prudhomme J, Le Roch K, Fairchild CR, Franzblau SG, Hay ME, Aalbersberg W, Kubanek J (2010) Bioactive bromophycolides R­U from the Fijian red alga Callophycus serratus. Journal of Natural Products 73:275-­278. doi: 10.1021/np900686w

Whalen KE, Lane AL, Kubanek J, Hahn ME (2010) Biochemical warfare on the reef: the role of glutathione S­ transferases in consumer tolerance of dietary prostaglandins. PLoS ONE 5:e8537. doi: 10.1371/journal.pone.0008537.

Lane AL, Mular L, Drenkard EJ, Shearer TL, Engel S, Fredericq S, Fairchild CR, Prudhomme J, Le Roch K, Hay ME, Aalbersberg W, Kubanek J (2010) Ecological leads for natural product discovery: Novel sesquiterpene hydroquinones from the red macroalga Peyssonnelia sp. Tetrahedron 66:455-­461. doi: 10.1016/j.tet.2009.11.042

Lane AL, Nyadong L, Galhena A, Shearer TL, Stout EP, Parry RM, Kwasnik M, Wang MD, Hay ME, Fernandez F, Kubanek J (2009) Desorption electrospray ionization mass spectrometry reveals surface­ mediated antifungal chemical defense of a tropical seaweed. Proceedings of the National Academy of Sciences 106:7314­-7319. doi: 10.1073/pnas.0812020106

Nyadong L, Hohenstein EG, Galhena A, Lane AL, Kubanek J, Sherrill CD, Fernandez F (2009) Reactive desorption electrospray ionization mass spectrometry (DESI MS) of natural products of a marine alga. Analytical & Bioanalytical Chemistry 394:245-­254. doi: 10.1007/s00216-009-2674-3

Poulson K, Sieg RD, Kubanek J (2009) Chemical ecology of the marine plankton. Natural Product Reports 26:729­-745.  doi: 10.1039/b806214p

Lane AL, Stout EP, Lin AS, Prudhomme J, Le Roch K, Fairchild CR, Franzblau S, Hay ME, Aalbersberg W, Kubanek J (2009) Antimalarial bromophycolides J­Q from the Fijian red alga Callophycus serratus. Journal of Organic Chemistry 74:2736-­2742. doi: 10.1021/jo900008w

Stout EP, Hasemeyer A, Lane AL, Davenport T, Engel S, Hay ME, Fairchild CR, Prudhomme J, Le Roch K, Aalbersberg W, Kubanek J (2009) Antibacterial neurymenolides from the Fijian red alga Neurymenia fraxinifolia. Organic Letters 11:225­-228. doi: 10.1021/ol8024814

Snell TW, Shearer TL, Smith HA, Kubanek J, Gribble KE, Mark Welch D (2009) Genetic determinants of mate recognition in Brachionus manjavacas (Rotifera). BMC Biology 7:60. doi: 10.1186/1741-7007-7-60

Thompson CH, Olivetti PR, Fuller MD, Freeman CS, McMaster D, French RJ, Pohl J, Kubanek J, McCarty NA (2009) Isolation and characterization of a high affinity peptide inhibitor of ClC­2 chloride channels. Journal of Biological Chemistry 284:26051-­26062.

Prince EK, Myers TL, Naar J, Kubanek J (2008) Competing phytoplankton undermines allelopathy of a bloom­forming dinoflagellate. Proceedings of the Royal Society B: Biological Sciences 275:2733­-2741. doi:10.1098/rspb.2008.0760

Prince EK, Myers TL, Kubanek J (2008) Effects of harmful algal blooms on competitors: allelopathic mechanisms of the red tide dinoflagellate Karenia brevis. Limnology & Oceanography 53: 531-­541.

Myers TL, Prince EK, Naar J, Kubanek J (2008) Loss of waterborne brevetoxins from exposure to phytoplankton competitors. Harmful Algae 7:762-­771.

Padove Cohen SA, Hatt H, Kubanek J, McCarty NA (2008) Reconstitution of a chemical defense signaling pathway in a heterologous system. Journal of Experimental Biology 211:599­-605.

Jiang RW, Lane AL, Mylacraine L, Hardcastle K, Fairchild CR, Aalbersberg W, Hay ME, Kubanek J (2008) Structures and absolute configurations of sulfate­ conjugated triterpenoids including an antifungal chemical defense of the marine green alga Tydemania expeditionis. Journal of Natural Products 71:1616­-1619. doi: 10.1021/np800307h

Jiang RW, Hay ME, Fairchild CR, Prudhomme J, Le Roch K, Aalbersberg W, Kubanek J (2008) Antineoplastic unsaturated fatty acids from Fijian macroalgae. Phytochemistry 69:2495­-2500.

Lane AL, Stout EP, Hay ME, Prusak AC, Hardcastle K, Fairchild CR, Franzblau SC, Le Roch K, Prudhomme J, Aalbersberg W, Kubanek J (2007) Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus. Journal of Organic Chemistry 72:7343­-7351.

Kubanek J, Snell TW, Pirkle C (2007) Chemical defense of the red tide dinoflagellate Karenia brevis against rotifer grazing. Limnology & Oceanography 52:1026­-1035.

Fuller MD, Thompson CH, Zhang ZR, McMaster D, French RJ, Pohl J, Kubanek J, McCarty NA (2007) State ­dependent inhibition of CFTR chloride channel by a novel peptide toxin. Journal of Biological Chemistry 282:37545­-37555.

Parker JD, Burkepile DE, Collins DO, Kubanek J, Hay ME (2007) Stream mosses as chemically­ defended refugia for freshwater macroinvertebrates. OIKOS 116:302-­312.

Prince EK, Lettieri L, McCurdy KJ, Kubanek J (2006) Fitness consequences for copepods feeding on a red tide dinoflagellate: deciphering the effects of nutritional value, toxicity, and feeding behavior. Oecologia 147:479-­488.

Lane AL, Kubanek J (2006) Structure­ activity relationship of chemical defenses from the freshwater plant Micranthemum umbrosum. Phytochemistry 67:1224-­1231.

Kubanek J, Prusak AC, Snell TW, Giese RA, Fairchild CR, Aalbersberg W, Hay ME (2006) Bromophycolides C­I from the Fijian red alga Callophycus serratus. Journal of Natural Products 69:731­-735.

Burkepile DE, Parker JD, Woodson CB, Mills HJ, Kubanek J, Sobecky P, Hay ME (2006) Chemically ­mediated competition between microbes and animals: microbes as consumers in food webs. Ecology 87:2821­-2831.

Snell TW, Kubanek J, Carter W, Payne AB, Kim J, Hicks MK, Stelzer CP (2006) A protein signal triggers sexual reproduction in Brachionus plicatilis (Rotifera). Marine Biology 149:763­-773.

Parker JD, Collins DO, Kubanek J, Sullards MC, Bostwick D, Hay ME (2006) Chemical defenses promote persistence of the aquatic plant Micranthemum umbrosum. Journal of Chemical Ecology 32:815­-833.

Kubanek J, Prusak AC, Snell TW, Giese RA, Hardcastle K, Fairchild C, Aalbersberg W, Raventos­Suarez C, Hay ME (2005) Antineoplastic diterpene­benzoate macrolides from the Fijian red alga Callophycus serratus. Organic Letters 7:5261-­5264.

Kubanek J, Hicks MK, Naar J, Villareal T (2005) Does the red tide dinoflagellate Karenia brevis use allelopathy to out­compete other phytoplankton? Limnology and Oceanography 50: 883-­895.

Prusak AC, O’Neal J, Kubanek J (2005) Prevalence of chemical defenses in freshwater macrophytes. Journal of Chemical Ecology 31:1145­-1160.

Barsby, T, Kubanek J (2005) Isolation and structure elucidation of feeding deterrent diterpenoids from the sea pansy Renilla reniformis. Journal of Natural Products 68:511-­516.

Thompson CH, Fields DM, Olivetti PR, Fuller MD, Zhang ZR, Kubanek J, McCarty NA (2005) Inhibition of ClC­2 Cl­ channels by a peptide component of scorpion venom Journal of Membrane Biology 208:65-­76.

John EA, Pollet P, Gelbaum L, Kubanek J (2004) Synthesis and antifeedant effect of 2,3,4­ tribromopyrrole. Journal of Natural Products 67:1929­-1931.

Kubanek J, Lester S, Fenical W, Hay ME (2004) Ambiguous role of phlorotannins as chemical defenses in the brown alga Fucus vesiculosus. Marine Ecology Progress Series 277:79­-93.

Kicklighter C, Kubanek J, Hay ME (2004) Do brominated natural products defend marine worms from consumers? Some do, most don’t. Limnology and Oceanography 49:430­-441.

Fuller MD, Zhang ZR, Cui G, Kubanek J, McCarty NA (2004) Inhibition of CFTR channels by a peptide toxin of scorpion venom. American Journal of Physiology – Cell Physiology 287:C1328­-C1341.

Kubanek J, Jensen PR, Keifer PA, Sullards C, Collins DO, Fenical W (2003) Seaweed resistance to microbial attack: A targeted chemical defense against marine fungi. Proceedings of the National Academy of Sciences USA 100: 6916­-6921.

Barsby T, Kicklighter, C, Hay ME, Sullards MC, Kubanek J (2003) Defensive 2­alkylpyrrole sulfamates from the marine annelid Cirriformia tentaculata [Polychaeta: Cirratulidae]. Journal of Natural Products 66:1110­-1112.

Kicklighter C, Kubanek J, Barsby T, Hay ME (2003) Palatability and defense of some tropical marine worms: Alykylpyrrole sulfamates as deterrents to fish feeding. Marine Ecology Progress Series 263:299­-306.

Taylor RB, Lindquist N, Kubanek J, Hay ME (2003) Intraspecific variation in palatability and defensive chemistry of brown seaweeds: effects on herbivore fitness. Oecologia 136:412­-423.

Kubanek J, Whalen KE, Engel S, Kelly SR, Henkel TP, Fenical W, Pawlik JR (2002) Multiple defensive roles for triterpene glycosides from two Caribbean sponges. Oecologia 131:125-­136.

Hay ME, Kubanek J (2002) Community and ecosystem level consequences of chemical signaling in the plankton. Journal of Chemical Ecology 28:2001­2016.

Bourdelais AJ, Tomas CR, Naar J, Kubanek J, Baden DG (2002) New fish­killing alga in coastal Delaware produces neurotoxins. Environmental Health Perspectives 110:465-470.

Naar J, Bourdelais A, Tomas CR, Kubanek J, Whitney PL, Flewelling L, Steidinger K, Lancaster J, Baden DG (2002) A competitive ELISA to detect brevetoxin from Karenia brevis (formerly Gymnodinium breve) in seawater, shellfish, and mammalian body fluid. Environmental Health Perspectives 110:179­-186.

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