Peer Reviewed Publications

29. Lavoie, S.; Gauthier, C.; Mshvildadze, V.; Legault, J.; Roger, B.; Pichette, A. (2015) Theoretical Calculations and ROESY NMR for the Diastereochemical Characterization of Cytotoxic Tetraterpenes Isolated from the Oleoresin of Abies balsamea. Submitted to Journal of Natural Products (np-2015-004929).

28. Lavoie, S.; Ouellet, M.; Fleury, P.-Y.; Gauthier, C.; Legault, J.; Pichette, A. (2015) Complete 1H and 13C NMR assignments of a series of pergalloylated tannins. Magnetic Resonance in Chemistry (doi:10.1002/mrc.4328)

27. Simard, F.; Gauthier, C.; Chiasson, É.; Lavoie, S.; Mshvildadze, V.; Legault, J.; Pichette, A. (2015) Antibacterial Balsacones J−M, Hydroxycinnamoylated Dihydrochalcones from Populus balsamifera Buds. Journal of Natural Products, 78: 1147-1153 (doi:10.1021/acs.jnatprod.5b00155).

26. Sylla, B.; Gauthier, C.; Legault, J.; Fleury, P.Y.; Lavoie, S.; Mshvildadze, V.; Muzashvili, T.; Kemertelidze, E.; Pichette, A. (2014) Isolation of a new disaccharide nucleoside from Helleborus caucasicus: structure elucidation and total synthesis of Hellecaucaside A and its β-anomer. Carbohydrate Research, 398: 80-89 (doi:10.1016/j.carres.2014.06.027).

25. Simard, F.; Legault, J.; Lavoie, S.; Pichette, A. (2014) Balsacones D-I, dihydrocinnamoyl flavans from Populus balsamifera buds. Phytochemistry, 100: 141-149 (doi:10.1016/j.phytochem.2013.12.018).

24. Oueslati, S.; Legault, J.; Lavoie, S.; Pichette, A. (2014) A new flavonol glycoside from the medicinal halophyte Suaeda fruticosa. Natural Product Research, 28: 960-966 (doi:10.1080/14786419.2014.900771).

23. Lavoie, S.; Legault, J.; Simard, F.; Chiasson, E.; Pichette, A. (2013) New antibacterial dihydrochalcone derivatives from buds of Populus balsamifera. Tetrahedron Letters, 54: 1631-1633 (doi:10.1016/j.tetlet.2012.12.012).

22. Lavoie, S.; Gauthier, C.; Legault, J.; Mercier, S.; Mshvildadze, V.; Pichette, A. (2013) Lanostane- and cycloartane-type triterpenoids from Abies balsamea oleoresin. Beilstein Journal of Organic Chemistry, 9: 1333-1339 (doi:10.3762/bjoc.9.150).

21. Lavoie, S.; Legault, J.; Gauthier, C.; Mshvildadze, V., Mercier, S.; Pichette, A. (2012) Abibalsamins A and B, two new tetraterpenoids from Abies balsamea oleoresin. Organic Letters, 14: 1504-1507 (doi:10.1021/ol300237f). Contribution highlighted in Natural Product Reports – Hot off the Press, 29: 617-621 (doi:10.1039/C2NP90016E).

20. Georges, P.; Legault, J.; Lavoie, S.; Grenon, C.; Pichette, A. (2012) Diterpenoids from the buds of Pinus banksiana lamb. Molecules, 17: 9716-9727 (doi:10.3390/molecules17089716).

19. Bourgou, S.; Pichette, A.; Lavoie, S.; Marzouk, B.; Legault, J. (2012) Terpenoids isolated from Tunisian Nigella sativa L. essential oil with antioxidant activity and the ability to inhibit nitric oxide production. Flavour and Fragrance Journal, 27: 69-74 (doi:10.1002/ffj.2085).

18. Bellila, A.; Tremblay, C.; Pichette, A.; Marzouk, B.; Mshvildadze, V.; Lavoie, S.; Legault, J. (2011) Cytotoxic activity of withanolides isolated from Tunisian Datura metel L. Phytochemistry, 72: 2031-2036 (doi:10.1016/j.phytochem.2011.07.009).

17. Collin, G.; Garneau, F.-X.; Gagnon, H.; Pichette, A.; Lavoie, S. (2010) Analysis of cymenes in essential oils: The case of Lepechinia meyeni (Walp.) epling. Journal of Essential Oil Research, 22: 310-313 (doi:10.1080/10412905.2010.9700333).

16. Pichette, A.; Eftekhari, A.; Georges, P.; Lavoie, S.; Mshvildadze, V.; Legault, J. (2010) Cytotoxic phenolic compounds in leaf buds of Populus tremuloides. Canadian Journal of Chemistry, 88: 104-110 (doi:10.1139/V09-151).

15. Thibeault, D.; Legault, J.; Gauthier, C.; Lavoie, S.; Bouchard, J.; Pichette, A. (2010) Acid-catalyzed E-ring expansion and isomerization of 3-acetylbetulin: synthesis of cytotoxic anhydrobetulin saponins. Synthetic Communications, 40: 213-221 (doi:10.1080/00397910902962886).

14. Gauthier, C.; Legault, J.; Piochon, M.; Lavoie, S.; Tremblay, S.; Pichette, A. (2009) Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products. Bioorganic & Medicinal Chemistry, 19: 2310-2314 (doi:10.1016/j.bmcl.2009.02.076).

13. Gauthier, C.; Legault, J.; Lavoie, S.; Rondeau, S.; Tremblay, S.; Pichette, A. (2009) Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins. Journal of Natural Products, 72: 72-81 (doi:10.1021/np800579x).

12. Simard, F.; Legault, J.; Lavoie, S.; Mshvildadze, V.; Pichette, A. (2008) Isolation and identification of cytotoxic compounds from the wood of Pinus resinosa. Phytotherapy Research, 22: 919-922 (doi:10.1002/ptr.2416).

11. Mskhiladze, L.; Legault, J.; Lavoie, S.; Mshvildadze, V.; Kuchukhidze, J.; Elias, R.; Pichette, A. (2008) Cytotoxic steroidal saponins from the flowers of Allium leucanthum. Molecules, 13: 2925-2934 (doi:10.3390/molecules13122925).

10. Gauthier, C.; Legault, J.; Lavoie, S.; Rondeau, S.; Tremblay, S.; Pichette, A. (2008) Synthesis of two natural betulinic acid saponins containing αl-rhamnopyranosyl-(12)-αl-arabinopyranose and their analogues. Tetrahedron, 64: 7386-7399 (doi:10.1016/j.tet.2008.05.029).

9. Garneau, F. X.; Collin, G.; Gagnon, H.; Bélanger, A.; Lavoie, S.; Savard, N.; Pichette, A. (2008) Composition of the essential oil of the rhizomes of Acorus calamus L. Journal of Essential Oil Research, 20: 250-254 (doi:10.1002/ffj.1136).

8. Bradette-Hébert, M. E.; Legault, J.; Lavoie, S.; Pichette, A. (2008) A new labdane diterpene from the flowers of Solidago canadensis. Chemical & Pharmaceutical Bulletin, 56: 82-84 (doi:10.1248/cpb.56.82).

7. Sylvestre, M.; Pichette, A.; Lavoie, S.; Longtin, A.; Legault, J. (2007) Composition and cytotoxic activity of the leaf essential oil of Comptonia peregrina (L.) Coulter. Phytotherapy Research, 21: 536-540 (doi:10.1002/ptr.2095).

6. Mshvildadze, V.; Legault, J.; Lavoie, S.; Gauthier, C.; Pichette, A. (2007) Anticancer diarylheptanoid glycosides from the inner bark of Betula papyrifera. Phytochemistry, 68: 2531-2536 (doi:10.1016/j.phytochem.2007.05.018).

5. Dufour, D.; Pichette, A.; Mshvildadze, V.; Bradette-Hébert, M. E.; Lavoie, S.; Longtin, A.; Laprise, C.; Legault, J. (2007) Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Ledum groenlandicum Retzius. Journal of Ethnopharmacology, 111: 22-28 (doi:10.1016/j.jep.2006.10.021).

4. Sylvestre, M.; Legault, J.; Lavoie, S.; Pichette, A. (2006) Investigation of leaf essential oil of Myrica gale L. from Quebec: purification and analysis of oxygenated fractions. Journal of Essential Oil Research, 18: 38-41 (doi:10.1080/10412905.2006.9699380).

3. Pichette, A.; Lavoie, S.; Morin, P.; Mshvildadze, V.; Lebrun, M.; Legault, J. (2006) New labdane diterpenes from the stem bark of Larix laricina. Chemical & Pharmaceutical Bulletin, 54: 1429-1432 (doi:10.1248/cpb.54.1429).

2. Pichette, A.; Liu, H.; Roy, C.; Tanguay, S.; Simard, F.; Lavoie, S. (2004) Selective oxidation of betulin for the preparation of betulinic acid, an antitumoral compound. Synthetic Communications, 34: 3925-3937 (doi:10.1081/SCC-200034788).

1. Lavoie, S.; Pichette, A.; Garneau, F. X.; Girard, M.; Gaudet, D. (2001) Synthesis of betulin derivatives with solid supported reagents. Synthetic Communications, 31: 1565-1571 (doi:10.1081/SCC-100104070).

Other Publications

2. Lavoie, S., (2015) Isolement et caractérisation de principes bioactifs d’Abies balsamea et de Cornus canadensis. PhD Thesis, Université du Québec à Chicoutimi, 555 pp.

1. Lavoie, S. (2001) Contribution à la synthèse de dérivés de l’acide bétulinique à partir du bétulinol extrait de l’écorce du bouleau blanc (Betula papyrifera). MSc Thesis, Université du Québec à Chicoutimi, 128 pp.

Patents

2. Legault, J.; Pichette, A.; Côté, I.; Lavoie, S. (2015) Use of plant extracts against herpes simplex virus. PCT International Patent Application 2015, WO2015010205 A1.

1. Pichette, A.; Legault, J.; Lavoie, S. (2008) Sesquiterpenes formulations, kits and methods of uses thereof. PCT International Patent Application 2008, WO2008144942 A1.

Communications

6. Lavoie, S.; Legault, J.; Pichette, A. (2014) Nouvels extraits de plantes antiherpétiques (oral communication). BENEFIQ, Sept. 23th 2014, Québec, Canada.

5. Lavoie, S.; Gauthier, C.; Legault, J.; Mshvildadze, V.; Pichette, A. (2014) Diastereosiomeric tetraterpenes from Abies balsamea oleoresin (oral communication). Trends in Natural Products Research, June 23th-25th 2014, Olomouc, Czech Republic.

4. Lavoie, S. (2014) Spectroscopies de masse et de résonance magnétique nucléaire appliquées à l’identification de pesticides (invited lecture). Université des Antilles et de la Guyane, Sept. 23th 2014, Pointe-à-Pitre, Guadeloupe, France.

3. Lavoie, S.; Pichette, A.; Cormier, D.; Chouinard, G.; Leblanc, M.; Riedl, B.; Caron, J.; Lord, D.; Legault, J. (2008) Valorisation des produits naturels présents dans les résidus d’écorces d’essences ligneuses du Québec par le développement d’utilisations dans le domaine des adhésifs et de l’agriculture (oral communication). Forum de transfert sur la forêt boréale et son écologie, April 8th, 2008, Chicoutimi, Québec.

2. Boumghar, Y.; El Mehdi, N.; Fournier, J.; Pichette, A.; Lavoie, S. (2003) Supercritical extraction of triterpenoids from birch bark (oral communication). 6e Symposium International sur les Fluides Supercritiques, April 2003, Versailles, France.

1. Lavoie, S.; Pichette, A.; Gaudet, D.; Garneau, F.X. (2001) Utilisation de composés triterpéniques naturels pour la préparation de produits potentiellement actifs dans divers champs thérapeutiques (poster). CONFOR, February 2001, Bar Harbor, ME, USA.